The difference between Si Jun Zi Wan and Ginseng & Atractylodes Macrocephalae is that Ginseng & Atractylodes Macrocephalae is made up of Si Jun Zi Wan, which has a wider scope of application; Si Jun Zi Wan specializes in strengthening the spleen, while Ginseng & Atractylodes Macrocephalae takes into account both strengthening the spleen and stopping diarrhea. Four Gentlemen Pill is mainly composed of Radix et Rhizoma Ginseng, Rhizoma Atractylodis Macrocephalae, Radix et Rhizoma Glycyrrhizae, Poria, and so on. Ginseng, Atractylodes Macrocephalae, Licorice, Poria, Chinese yam, Semen Coix lacryma, Lentinus edodes, Semen Aristolochiae, Lotus Seed and Platycodon Grandiflorus are the main ingredients in Sizunzi Pill. Sijunzi Pill benefits qi and strengthens the spleen, and can be used to treat conditions such as deficiency of spleen and stomach qi, loose stools (scanty and unformed feces), and lack of desire for food and drink, etc. It specializes in strengthening the spleen, and is the basic medicine for treating deficiency of spleen and stomach qi. Ginseng Ling Bai Zhu San benefits qi, strengthens the spleen and stops diarrhea by exuding dampness, and is the main formula for treating spleen deficiency with dampness, and can also replenish the lung qi, so in addition to treating spleen and stomach qi deficiency and loose stools with little food, it can also be used for treating lung deficiency with prolonged coughing and other conditions. The adverse reactions as well as contraindications of these two drugs are not yet known. However, during the period of consumption, try to eat less spicy and stimulating food that is not easy to digest, and should not be taken by people who have a cold or fever. These two drugs are applicable to slightly different diseases. When using the combination of the body’s condition, under the doctor’s diagnosis to choose the appropriate drug treatment, avoid taking the drug privately.