High serum inorganic phosphorus means that the concentration of inorganic phosphorus in the serum is outside the normal range. Common diseases with high serum inorganic phosphorus include: first, endocrine system diseases such as primary hypoparathyroidism and secondary hypoparathyroidism caused by other diseases. When hypoparathyroidism, in which the concentration of calcium ions is reduced, there is an increase in the concentration of inorganic phosphorus. Second, impaired inorganic phosphorus excretion is common in all kinds of acute renal failure as well as chronic renal failure. Regardless of the type of renal failure, it will lead to a decrease in inorganic phosphorus excretion, causing a high serum inorganic phosphorus concentration. Third, increased intake of serum inorganic phosphorus, such as excessive intake of vitamin D, which promotes intestinal absorption of calcium and phosphorus, can cause an increase in blood phosphorus and inorganic phosphorus. Finally, diseases such as multiple myeloma, healing phase of fracture, and acute liver necrosis can also result in high serum inorganic phosphorus.