Large vessel occlusion can cause acute poor cerebral perfusion, brain tissue has limited tolerance to ischemia, and in general, complete occlusion of brain tissue for more than 5 minutes can cause apoptosis and necrosis. With the prolongation of time, the harm gradually increases, the core infarcted area, the function is gradually irreversible, the infarcted area area gradually increases, and in severe cases, it can involve the key nerve centers. If efforts are made to open the blood vessels within the golden time window, cerebral perfusion can be improved in most of the ischemic regions of cerebral infarction, benefiting the patients.