Rib pain has various causes, such as trauma, costochondritis, etc., need to take different drugs according to the cause of the disease, such as antibiotics, non-steroidal anti-inflammatory drugs, etc., the use of drugs follow the doctor’s instructions. 1. If rib pain is caused by trauma in the chest and rib area, drugs such as ibuprofen can be chosen for anti-inflammatory and pain relief for rib area and chest soft tissue injuries, and antibiotics can be used as appropriate to prevent infection, such as ceftriaxone. If rib fracture occurs, non-steroidal anti-inflammatory drugs such as acetaminophen can be used, depending on the condition of the need for surgery or conservative treatment. 2. If it is caused by costochondritis, intercostal neuralgia, etc., non-steroidal anti-inflammatory drugs such as ibuprofen can be taken. 3. If the pain is caused by osteoporosis, calcium, vitamin D and other nutrients should be supplemented, and analgesic treatment can be provided. Rib pain should be consulted in time to clarify the cause of the disease and treated under the guidance of the doctor, so as to avoid delaying the condition. Drugs should be used under the guidance of a doctor to avoid self-medication.