The ercc gene is an important repair gene member of the human body’s family of important nucleotide excision repair proteins that are expressed to repair DNA damage. Nucleotide excision repair is an important method of DNA damage repair, and the ercc gene is an important gene member. low expression of the ercc gene often carries with it increased genetic instability and diminished DNA repair, resulting in a malignant phenotype of the tumor. Mutation or loss of ercc may cause corresponding diseases, such as coloring dry skin disease, cancer, hair dystrophy, etc. The ercc gene is associated with a variety of cancers, and detection of ercc expression is beneficial for patients to be treated with appropriate chemotherapy.