Cervical peri-shoulder pain can be caused by aseptic inflammation or directly caused by cervical spondylosis, and the fastest ways to relieve it include physical therapy, medication, and surgery. 1. Aseptic inflammation: Aseptic inflammation in the neck and shoulder can lead to pain symptoms in the cervical spine and shoulder area. Patients first need to correct the wrong posture, avoid prolonged head down, and do more backward leaning and chest expanding exercises to relieve the fatigue of the soft tissues of the neck and shoulder; they can also choose physical therapy to accelerate the blood circulation of the neck and shoulder; and they can also take ibuprofen and loxoprofen orally to relieve the pain. 2. Cervical spondylosis: Cervical spondylosis can cause compression of the nerves that innervate the neck and shoulder area, resulting in neck and shoulder pain symptoms. Patients can take oral vitamin B1, methylcobalamin and other drugs to nourish peripheral nerves; can also be static drip mannitol, dexamethasone and other drugs to reduce the edema of the nerve root compression; conservative treatment is ineffective, the emergence of limb muscle strength, sensory loss of patients can consider surgical intervention. If the symptoms of cervical spine and shoulder pain are not relieved, or accompanied by other symptoms, patients should go to the hospital in a timely manner, and after clarifying the cause of the pain, targeted treatment should be given. All of the above medications should be used under the guidance of a doctor to avoid self-medication.