Left chest pain on pressure may be caused by thoracic spine fracture, costochondritis, tuberculous pleurisy and other diseases. 1. Thoracic spine fracture: the occurrence of this disease is related to direct violence such as impact, direct pressure of heavy objects, followed by indirect violence caused by falling from a high place and hitting the shoulder with heavy objects. When the patient’s thoracic vertebrae are damaged, there will be pain, swelling, activity limitation and other symptoms, and some patients have the manifestation of pain in the left chest by pressing. 2. Costochondritis: the etiology of this disease is not clear, it may be related to viral infection, chronic strain, cartilage nutritional disorders, strenuous exercise and so on. The main symptom is anterior chest pain, pressure pain when pressing rib cartilage, which can be manifested as left chest pain when pressing. 3. Tuberculous pleurisy: this disease is mainly caused by Mycobacterium tuberculosis infection, but can also be secondary to abdominal tuberculosis, vertebral tuberculosis and other diseases, which can be induced by low immunity, and some patients will have chest pain, dyspnea, fatigue, fever and other symptoms. It is recommended that patients with left chest pressure pain go to the hospital to improve a series of examinations to clarify the cause of the disease.