The pain in the stomach after oral administration of misoprostol tablets belongs to the pharmacological effect of the drug, the reason is that it prompts the uterine smooth muscle to contract strongly resulting in lower abdominal pain. Misoprostol, belonging to the prostaglandin class of drugs, is mainly used to terminate early pregnancy, with the effect of enhancing uterine tension and intrauterine pressure, softening the cervix. It promotes uterine contractions by exciting the uterus, softening the cervix, and discharging intrauterine pregnancy products, accompanied by lower abdominal pain and discomfort caused by contractions. Its main adverse effects are loose stools or diarrhea, and it is contraindicated in people who are allergic to prostaglandins. In addition, it still has the pharmacological activity of E-type prostaglandins, which can mildly stimulate the smooth muscle of the gastrointestinal tract, while large doses can inhibit the secretion of gastric acid. The use of misoprostol tablets is recommended under the guidance of a doctor or pharmacist, not self-medication to avoid adverse reactions.