The common causes of heart discomfort when lying down are heart failure, gastroesophageal reflux disease, etc. Patients should consult a doctor in time to clarify the cause of the disease and then treat it. 1. Heart failure: the heart’s pumping function decreases, the volume of cardiac output can not meet the body’s needs, patients will have difficulty in breathing when lying down, chest tightness and other symptoms. If necessary, under the guidance of the doctor to use captopril, hydrochlorothiazide and other drugs for treatment. 2. Gastroesophageal Reflux Disease (GERD): Lying down with an uncomfortable heart may also be gastroesophageal reflux disease (GERD) caused by heartburn, and such patients may also have acid reflux, belching (hiccups), and a feeling of a foreign body in the throat. It can be treated with drugs such as mosapride under the guidance of a doctor. Appear lying heart uncomfortable situation need to consult a doctor in time, follow the doctor’s instructions for treatment.