Anti-SSA antibody, also known as anti-Ro antibody, is found mainly in the cytoplasm and is an antibody belonging to the spectrum of anti-nuclear antibodies. It can be detected in the test anti-EA series, with molecular weights of 52KD and 60KD, and is mostly associated with dry syndrome. Anti-SSA antibodies can exist alone or in combination with SSB antibodies and are often seen in connective tissue diseases such as dry syndrome, systemic lupus erythematosus, rheumatoid arthritis, and can also cause neonatal lupus and congenital atrioventricular block, and are often associated with symptoms such as vasculitis, lymph node enlargement, leukopenia, photosensitivity, skin lesions, and purpura.