1. Secretory otitis media can cause adhesive otitis media if not treated in time, leading to continuous hearing loss and even irreversible hearing damage. Lin Xing, Department of Otolaryngology, Second Hospital of Nanping City, Fujian Province 2. Acute purulent otitis media may mostly turn into chronic otitis media if the treatment is not timely and thorough. In addition, if chronic rhinitis, chronic sinusitis and chronic tonsillitis exist, bacteria may repeatedly invade the middle ear cavity and otitis media latent down leading to chronic otitis media. There is the appearance of ear pus, repeatedly, and sometimes the pus is mixed with bloody secretions; in addition, there is tinnitus and hearing loss, and critical acute and chronic otitis media may cause intracranial and extracranial complications, such as: facial nerve palsy, meningitis, brain abscess, and labyrinthitis. Very few patients can lead to the development of middle ear cancer.