When applying mannitol externally to the breasts, it is usually necessary to break the mannitol and put it into a gauze bag and wrap it around the breasts, not too thick, a thin layer will do. Put the gauze bag on the lower side of the breast, after a period of time the mannite will harden and can be replaced again, 3-4 times a day, each time at an interval of 2-3 hours, after removing the mannite to wipe the breast with a towel to test clean, so that the skin is exposed. Mannitol has the effect of reducing swelling, relieving pain, activating blood circulation, removing heat and softening hardness. Mannitol is commonly used clinically to apply to the breasts in conjunction with the return of breast milk and to take vitamin B6 orally. mannitol can relieve the swelling and pain associated with milk rise without any side effects. Patients should also drink less soup with high protein and fat to reduce the production of milk. In addition, external application of mannitol to the breasts can also be used as an aid in the treatment of breast diseases such as mastitis and breast enlargement.