Perimenopause refers to the period of time before and after menopause in women, which usually begins at the age of 40 years with the onset of clinical manifestations of reproductive endocrinology and biology, and ends 12 months after the cessation of menstruation. Therefore, it is generally normal to enter perimenopause at the age of 44. Perimenopause is a period of normal physiologic change. Most women do not experience any discomfort, while some will experience some discomfort. Functional uterine bleeding, senile vaginitis, neuropsychiatric symptoms such as agitation and irritability, fluctuating blood pressure, osteoporosis, etc., are the main symptoms for a few women. If perimenopausal women experience any physical or psychological discomfort, they should go to the hospital in a timely manner and complete the relevant examinations according to the doctor’s instructions, so as to clarify the diagnosis of the disease and receive standardized treatment. Perimenopausal women can take appropriate measures, such as maintaining a happy mood, eating a nutritious diet, avoiding alcohol and tobacco, etc., so as to pass through this special period smoothly. Thus, they can pass through this special period smoothly.