Small and itchy blisters on the toe crevices are clinically considered as two diseases: 1) Tinea pedis, which is what we call foot fungus; 2) Eczema of the foot, both of which may appear as blisters in the toe crevices and are accompanied by itching. In general, tinea pedis tends to develop on one foot first and spread to the other foot after a long time, because the other foot is also infected by the fungus of this foot, and at the same time, if a microscopic examination of the fungus is done, the mycelium or spores can be detected. The eczema on the foot is symmetrically distributed and occurs at the same time, also accompanied by varying degrees of itchiness, there is no positive finding in the fungal microscopy, it is recommended to consult the dermatology department in a regular professional hospital.