Type 2 diabetes is caused by both insulin deficiency and insulin resistance. The following points should be noted when using medication for type 2 diabetes: First, lifestyle intervention is the basis of treatment, and dietary and exercise therapy for diabetes should be adhered to throughout the treatment of diabetes. Second, the initial onset of type 2 diabetes mellitus patients who do not have very high blood sugar can be given biguanide preparations, glycosidase inhibitors, such as acarbose, insulin sensitizer pioglitazone and other drugs, taken alone or in combination. Third, if blood glucose rises significantly and the above drugs cannot be controlled, insulin promoters, such as sulfonylureas or glinides, can be combined. Fourth, if the combination of hypoglycemic drugs, blood glucose control still does not meet the standard, or long duration of the disease combined with acute and chronic type 2 diabetes, as well as patients with significant wasting, they need to be treated with insulin. Five, in the process of diabetes treatment should pay attention to monitoring blood sugar to avoid serious hypoglycemia. Adjust the medication under the guidance of the doctor, not to adjust the medication without permission, and not to stop the medication on your own.