Flurbiprofen ester pain relief time is 6-8 hours after the drug, flurbiprofen ester is a non-steroidal anti-inflammatory, analgesic drugs, has the ability to target analgesia, can inhibit the synthesis of prostaglandins in the body, and play an analgesic effect. The blood concentration can be reached in about 10 minutes after intravenous application, and the half-life is about 6 hours, while nearly half of the flurbiprofenate will be excreted from the kidneys through urine after 24 hours. Flurbiprofen ester is commonly used as postoperative and tumor analgesia, especially for artificial knee replacement after analgesia, pain relief effect is obvious, and there is no opioids are prone to cause nausea, vomiting side effects. For patients with peptic ulcer, flurbiprofen ester can not be used, can aggravate the condition of the ulcer and cause gastrointestinal bleeding.