Bivalirudin and Glucosamine Hydrochloride both have some therapeutic effect on osteoarthritis, the specific efficacy varies from person to person, so it is not possible to judge whose efficacy is better. 1. Bivalirudin is suitable for the treatment of osteoarthritis of hip and knee joints. Contraindications to the use of the drug include those who are allergic to the product or have a history of allergy to anthraquinone derivatives, those with unknown cause of abdominal pain, those with inflammatory bowel disease, those with intestinal obstruction or pseudo-obstruction, and those with hereditary lactose intolerance. The most common adverse reactions are diarrhea, abdominal pain, frequent bowel movements, soft stools, and flatulence. 2. Aminoglucosamine hydrochloride can be used to relieve osteoarthritis pain, improve joint movement, etc. It has preventive and curative effects on osteoarthritis in all parts of the body, specifically including relieving and eliminating pain, swelling and other symptoms, and improving the function of joint movement. Contraindications include hypersensitivity to the product, adverse reactions include abdominal pain, belching (hiccups), nausea, diarrhea, constipation, abdominal distension, headache, fatigue, drowsiness, rash, itching and so on. 3. Both bisacodyl and aminoglucose hydrochloride can be used in the treatment of osteoarthritis, and it is not possible to judge clearly who is more effective in the treatment of osteoarthritis because of the individual differences in the group of people who are eligible for the drug. The specific use of drugs should be carried out under the guidance of specialists, not unauthorized use of drugs.