Eyelid swelling when waking up in the morning is firstly considered to be caused by physiological factors, and secondly, allergies and systemic diseases such as nephrotic syndrome should also be considered. 1. Physiological factors: staying up late, drinking too much water before going to bed, crying, sleeping in the wrong position, etc., can cause eyelid swelling in the morning, generally in the eyes can be relieved after getting enough rest, without special treatment. 2. Allergy: if you sleep at night on the pillow or pillowcase on the items allergies, caused by eyelid allergy, can lead to increased permeability of local capillaries, when the blood vessels in the material leaked into the tissue space, the morning wake up eyelid swelling. 3. Nephrotic syndrome: nephrotic syndrome can cause glomerular injury, resulting in impaired glomerular filtration barrier, so that the water metabolism is abnormal, i.e., sodium retention, so the eyelids will be swollen when you wake up in the morning. 4. Heart failure: heart failure can cause the body circulation and pulmonary circulation stagnation, so that the body of water circulation obstacles, can lead to generalized swelling, may appear in the morning wake up eyelids swollen situation. Eyelid swelling in the morning, if a long time no relief or accompanied by other body discomfort, must go to the regular hospital to identify the cause of the disease, and actively cooperate with the professional doctor’s treatment.