Mildly elevated premenopausal TOMA index may be a premenopausal phenomenon, and if the elevation is more pronounced, it is necessary to consider whether it is ovarian cancer. The normal range of ROMA index is 0-11.4% in premenopause and 0-29.9% in postmenopause, so a mildly elevated premenopausal ROMA value may be a premenopausal phenomenon. If the ROMA value is significantly elevated, further CA125, magnetic resonance or CT examination, HE4 or human epididymal protein 4 examination, etc., are needed to confirm whether there is ovarian carcinoma. If the premenopausal ROMA index is high, it is necessary to go to the hospital as soon as possible, and the doctor will formulate an individualized diagnosis and treatment plan according to the specific condition, so as to avoid delaying the condition.