Ulcers with a worm-like appearance are caused by trauma, crush injury, trauma and other direct injury to the human body, and then feel the poisonous evil, resulting in abnormal operation of qi and blood, resulting in skin ulcers, and can not do a good job of skin protection or away from the stimulating environment, long treatment, seriously endangering the health and quality of life of patients. What tests can confirm the appearance of ulcers with worm-like appearance? For the treatment of any disease we should combine medical history, current condition and laboratory tests to better diagnose the condition, and ulcers with a wormy appearance are no exception. Ulcers with worm-like appearance are mostly seen in scar carcinoma, which starts with local itching and sensory allergy in the scar area, and then ulcers appear after the scar is broken, or the ulcers gradually expand and break down from small papules, and on the edge of the ulcers that do not heal for a long time, they gradually bulge and appear keratinized proliferation or papillary hyperplasia changes. The appearance of the ulcer is crater-like, cauliflower-like and worm-like, and it is easy to bleed when touched, and the surface can be covered with pus moss and the secretion is foul-smelling. The development of the lesion is slow, because the cancer cells are surrounded by tough and dense scar tissue, so it is generally not easy to spread and metastasize, but once it expands to normal tissue, it will spread rapidly and metastasize. 1.Examination of medical history Understanding the medical history of ulcer patients should focus on the causes of ulcers, generally speaking, it should include patients’ age, gender, occupation and history of unclean sexual intercourse. Because ulcers are often secondary damage, it is particularly important to understand the characteristics of the initial damage to the lesions in the present history, which can often provide diagnostic clues. It is also important to know the location of the lesions, the speed of development, changes, the duration of the disease and the use of medication, and previous diseases. 2. Physical examination should pay attention to the general condition of the patient and the location, distribution, size, number, color and clarity of the edges of the ulcer. The shape, base and surface secretions should be noted. Histopathology is a commonly used diagnostic method to differentiate tumors, vasculitis and general inflammatory ulcers. Bacterial culture and fungal examination can help in the diagnosis of infectious diseases.