For the treatment of Horner syndrome, there are two principles: First, etiological treatment. Anti-infective treatment is performed for inflammation, while chemotherapy, radiotherapy and surgery are performed for tumors. Second, symptomatic support treatment. The principle of medication: antibiotics are used for inflammation, and oral cotrimoxazole, ciprofloxacin and vincristine can be taken for mild cases. For severe infection, penicillin and vincristine are used for static injection or drip, or antibiotics are selected according to drug sensitivity test. For tumor patients, use chemotherapeutic drugs, such as Adriamycin, Vincristine, etc. For the primary disease, symptomatic support for the primary disease and immune enhancement therapy are taken.