To determine whether the white spots on the face are vitiligo, diagnosis can be made through symptoms, laboratory tests, pathology, and filtered ultraviolet lamp (Wood lamp) examination, dermoscopy and so on. 1. Symptoms: vitiligo typical skin lesions for milky white or porcelain white pigment loss spots, border is clear, the size varies, can be presented as round, oval, irregular, linear, etc.; can be a single, distributed, generalized, isolated, etc., in the white spots in the hair can be normal or whitened. 2. laboratory examination: clinical diagnosis of vitiligo can be carried out through the detection of anti-thyroglobulin antibodies and other related antibodies, if the anti-thyroglobulin antibodies more than 40U / ml, the antibody is high, suggesting that the existence of autoimmune diseases, but also lead to the emergence of vitiligo. 3. Pathological examination: clinically atypical vitiligo, can with the help of skin lesions histopathological examination clear diagnosis. Typical white patches of white skin melanocytes and pigment granules completely missing, and DOPA or Melan-A staining negative. 4. filtered ultraviolet lamp (Wood lamp) examination: help pigmented skin disease diagnosis, vitiligo patients in the progressive stage of skin lesions for gray-white fluorescence, border is not clear; the stable stage for the bright blue-white fluorescence, border is clear. 5. Dermoscopy: show the naked eye can not be observed on the surface of the skin lesions and subcutaneous structural features, the examination, visible around the hair follicle residual pigmentation of some vitiligo lesions is helpful in the diagnosis. Once the face of white spots, you can go to the regular hospital as soon as possible to improve the relevant examination, in order to identify and diagnosis, active treatment, so as not to miss the condition.