The five highs are hyperglycemia, hypertension, hyperlipidemia, hyperviscosity, and hyperuricemia. The five highs are very harmful to human health, especially behind the scenes to induce diabetes complications. 1, high blood sugar in high five can produce “high glucose toxicity” which can harm the whole body cells of diabetic patients; 2, high blood viscosity in high five can increase the resistance of blood flow, slow down the speed of blood flow and induce myocardial infarction; 3, abnormal blood lipids in high five can easily cause the rise of blood viscosity and atherosclerosis; 4, high blood pressure in high five can cause cerebrovascular disease, hypertension, hyperlipidemia, hypovolemia and hyperuricemia. Hypertension is the main risk factor causing cerebrovascular disease, coronary heart disease, heart failure and kidney damage; 5, hyperuricemia can damage the arterial intima, etc. It can be seen that the five highs are closely related to the complications of diabetes.