Constipation after taking Ginseng and Atractylodes Macrocephalae may be related to the condition, dosage, diet and other factors. Ginseng and Atractylodes Macrocephalae is composed of ginseng, atractylodes, poria, lentils, and Chinese yam, etc. It can treat diarrhea, poor diet, scanty stools, and fatigue and shortness of breath associated with spleen deficiency and dampness. Adverse reactions and contraindications are not clear. It is not suitable for patients with fever and cold. Avoid indigestible food while taking the medicine. If the drug is taken in the absence of the right medicine, it may cause adverse reactions such as constipation. Because Ginseng Ling Bai Zhu San has a warming effect, if it is taken for a long time or in excess, it may lead to the generation of internal fire and constipation. Diet, if eating spicy and stimulating food, it will easily lead to internal fire and heat, causing dry stools, or food accumulation (food that is indigestible and stops accumulating in the stomach) after not being able to be digested, which may also cause constipation. Taking Ginseng and Atractylodes Macrocephalae requires doctor’s guidance and standardized use, and after constipation or other adverse reactions occur, consult a doctor for consultation and treatment in a timely manner.