It goes without saying how important the skull is, but nowadays problems like skull defects are very common. When the skull is missing, the intracranial tissues have no umbrella, and may be attacked by the outside world at any time, and some unexpected problems may occur. Therefore, it is important to pay attention to cranial defects, and it is crucial to go to a regular hospital as soon as possible to have cranial bone repair surgery. When going to the hospital for cranial repair surgery, patients should pay attention to the choice of repair materials, the right choice of materials to achieve better safety and results. Nowadays, most hospitals widely use titanium mesh material, which is an improvement over earlier materials. However, there are still some disadvantages and side effects: first, titanium mesh material is easily affected by the external temperature, fast thermal conductivity, the patient’s scalp will feel uncomfortable; second, titanium mesh material is taken to cover the repair, the scalp stimulation; third, titanium mesh material’s hardness is not very good, easy to be deformed by the impact of external forces; fourth, titanium mesh material is a metal material, which affects the postoperative CT, MRI and other medical, producing artifacts. produce artifacts. Fourth, titanium mesh material is a metal material, which will affect the postoperative CT, MRI and other medical, resulting in artifacts. Moreover, titanium mesh material has the risk of exposure if infection or rejection occurs. There are so many disadvantages of titanium mesh materials that it is important to choose a material with as few side effects and good results as possible before surgery. In contrast, no significant side effects have been found with polyether ether ketone cranial repair, which is a very advanced polymer material commonly known as PEEK material. It has many advantages and avoids all the above mentioned problems that may occur with titanium mesh material, and the recovery effect after surgery is very good.