Compression urticaria is a type of urticaria that can be treated with cetirizine. Compression urticaria is a skin allergy that produces redness, pimples, itching, burning and other skin irritation symptoms at the site of pressure under external forces, and in some patients, it may also lead to systemic symptoms such as dizziness and fever. It occurs in situations such as prolonged standing or persistent pressure on body parts and is classified as induced urticaria. The primary treatment for this condition is the use of antihistamines, such as cetirizine and other medications. Cetirizine is indicated for allergy-induced skin itching and hives, seasonal rhinitis, and perennial allergic rhinitis. The main use of this medication is for adults to take 1 tablet once a day or half a tablet twice a day. For children, 6-12 years of age, 1 tablet once a day or ½ tablet twice a day; 2-6 years of age, ½ tablet once a day or ¼ tablet twice a day. Occasional mild and transient adverse reactions such as headache, dizziness, drowsiness, dry mouth, abdominal discomfort, etc. After taking the drug, it is forbidden to take it in patients who are allergic to cetirizine and with renal impairment. Pressure urticaria in the use of cetirizine treatment, need to be taken under the guidance of a doctor, can not be self-medication, in order to avoid adverse reactions.