Clinical symptoms and treatment of aspirin intolerance triad

  Since people do not know about aspirin intolerance triad disease, of course they are even less aware of the symptoms of the disease. What are the symptoms of aspirin intolerance triad? Once the disease is diagnosed, how should it be treated? To answer these questions, please take a look at the following.  The disease is often vasomotor at first, patients may have more watery nasal discharge with eosinophils in the nasal secretions, later there may be progressive hypertrophic sinusitis and nasal polyp formation, and asthma may occur after middle age. Patients taking aspirin and other antipyretic and analgesic drugs can often trigger rhinitis or asthma attacks, and very few patients can have severe reactions, such as chest tightness, throat obstruction, or even shock and death.  According to the clinical manifestations, the disease has the following characteristics: ① There are often recurrent episodes of sinusitis. (2) Recurrence of nasal polyps is very easy after surgery. ③Asthma is severe and often adrenocorticotropic hormone dependent. ④ Food coloring additives (tartiazine) and preservatives (benzyl alcohol) also often cause asthma attacks and aggravate nasal polyps.  When the symptoms of the disease are known, the patient will go to the hospital first to check the diagnosis and then treat the symptoms, the treatment plan is as follows: 1. For nasal polyps and asthma attackers, avoid using antipyretic and analgesic drugs and eating foods with color additives or preservatives.  2. For severe asthma, prednisone 30mg/d can be given orally, and after asthma control, it can be replaced by intranasal aerosol aerosol with dipropanol chlordimethasone, 3 times a day, one spray each time, total 400mg daily. 3. For large nasal polyps, prednisone 30mg/d can be given orally for one week, and then replaced by intranasal drops with tretinoin or intranasal aerosol with dipropanol chlordimethasone after volume reduction. .  4. nasal polyps with large nasal congestion, after the above treatment is still not improved, can consider surgery to remove. Janhi-Alanko et al. (1989) reported that 59% of patients had improved asthma after surgery, and 12% had worsened asthma.  Warm reminder: The above is an introduction to the clinical symptoms and treatment of aspirin intolerance triad. However, in life, few people discover the symptoms of the disease in time, and the disease is usually discovered only after the disease is serious and checked in the hospital, which brings obstacles to the treatment of the disease. Therefore, it is important to have regular annual health checkups so that symptoms of the disease can be detected in advance.