Blood creatinine, urinary protein are high can be reduced by themselves according to the analysis of the cause of the disease, physiological causes of elevation, can be recovered by themselves; for pathological causes of elevation, need to comply with the doctor’s advice and timely symptomatic treatment, can not be reduced by themselves. 1. Physiological reasons: if recently eat too much meat or after strenuous exercise may cause blood creatinine, urine protein rise, remove the triggers can be recovered. 2. Pathological reasons: such as chronic glomerulonephritis, diabetic nephropathy, hypertensive nephropathy and other diseases lead to kidney damage caused by blood creatinine, urinary protein increased, should follow the doctor’s instructions to clarify the cause of the disease, symptomatic treatment, control creatinine, urinary protein further growth, slow down the progress of kidney disease, can not be lowered on their own. It is recommended that patients with elevated creatinine and urinary protein should go to regular hospitals in time, under the guidance of doctors to carry out appropriate examinations, and then follow the doctor’s instructions to standardize the treatment after clarifying the causes.