Are you taking the right lipid-lowering drugs?

Lipid testing is one of the most common blood tests that are performed during medical consultations and is one of the more common abnormalities in the general population. Lipid tests are closely related to our diet and lifestyle habits. First of all, let’s take a look at blood lipids: Here we will mainly talk about the blood lipid tests that are often measured by patients in hospitals. Elevated triglycerides, mostly seen in diabetes and metabolic syndrome, can lead to pancreatitis in severe cases. Total cholesterol, which tends to rise gradually with age, stops rising in older people after the age of 70 and declines in some cases, and is higher in postmenopausal women than in men of the same age. High-density lipoprotein, which is dominated by apolipoprotein a1, accounts for 65% to 75%. It is a finger protein with anti-atherosclerotic properties in the body. Low-density lipoprotein, his elevation is considered a high-risk factor for coronary heart disease and has an atherogenic effect. apolipoprotein b, reflects the amount of low-density lipoprotein in the blood. Lipoprotein a studies have found that its elevation is also associated with coronary artery disease. If the patient is predominantly high in triglycerides, then a lipid-lowering drug of the fibrate class is preferred, such as benzofibrate or fenofibrate patients, and if high LDL is predominant, statins are preferred for treatment. Commonly used clinically are atorvastatin, resulvastatin. Statins are secondary prevention drugs for cardiovascular disease, which can stabilize plaque, lower blood lipids, improve vascular endothelial function, and lower LDL while lowering cholesterol, as well as raise HDL. If both triglycerides and LDL are high, patients can take oral fibrates to lower triglycerides first, and after triglycerides are basically normal, change to oral statins, it is better not to take both types of drugs at the same time to avoid rhabdomyolysis. Elevated lipoprotein a is generally not treated specifically. If the elevation is more pronounced, then oral niacin extended-release tablets can be taken to improve it. The ratio of apolipoprotein b to apolipoprotein a1 in this is also of some significance in predicting coronary heart disease.