HPV vaccination is not recommended for women after the age of 45. HPV vaccine is divided into bivalent, quadrivalent and nine-valent, and its suitable vaccination age are all 9-45 years old, it is recommended that the appropriate age group complete the vaccination as early as possible, the earlier the vaccination time the better the effect. For women after the age of 45, HPV vaccination is not recommended, and its effect may not be as good as that of the appropriate age group. The HPV vaccine is a preventive vaccine that does not cure HPV infection and related diseases, does not prevent all HPV types of infection, and does not stop HPV infection from progressing to disease progression. Therefore, regular cervical cancer screening is still needed after HPV vaccination. HPV vaccination is contraindicated in persons with hypersensitivity to the active ingredient of the vaccine or to any of the excipient components, and persons with symptoms of hypersensitivity after injection of this product should not be revaccinated with this product.