The fastest way to cure knee spurs is not a scientific question. At present, the clinical treatment for knee spurs according to its severity generally adopts a stepped program for treatment, such as general treatment to reduce the weight of the knee joint, physical therapy, such as ultrasound, medication, such as non-steroidal anti-inflammatory and analgesic drugs or surgical treatment, such as minimally invasive arthroscopic surgery of the knee. For the early stage of knee spurs, which do not produce obvious clinical symptoms, it is only necessary to pay attention to changing the daily life style, such as avoiding climbing stairs and mountains, etc., to reduce the weight of the knee joint and stress, and pay attention to warmth, avoiding cold, and reducing weight. If the patient has mild pain and discomfort, non-steroidal anti-inflammatory and analgesic drugs such as celecoxib and drugs that nourish the joint cartilage such as glucosamine capsules can be used together with physiotherapy. For moderate knee spurs, sodium vitreous acid injection and arthroscopic cleaning of the knee joint can be used. If the knee spurs are concentrated on one side of the knee joint and the articular cartilage is not too badly worn out, periprosthetic osteotomy of the knee can also be used for treatment. If the lesion is located on the medial or lateral side of the knee and the cartilage is severely worn, unicondylar replacement can be used, and if the knee spur causes the whole knee joint lesion and is more serious or causes obvious deformity, total knee replacement is needed. The use of medication should be in accordance with the doctor’s instructions.