Stage 2 renal clear cell carcinoma can be actively intervened by surgical treatment and targeted therapy. Stage II renal clear cell carcinoma refers to T2N0M0 stage, i.e. the tumor is confined to kidney without regional lymph node metastasis and distant metastasis, etc. It is usually treated by surgical resection. 1. Surgery: Stage 2 renal cancer is confined renal cancer, surgery is preferred to remove the local lesion completely, and if necessary, extended resection is also needed, according to the size of the tumor, laparoscopic surgery or open surgery can be chosen, radical nephrectomy is usually recommended. 2. Targeted therapy: Sunitinib, Axitinib and other drugs can be used as prescribed by doctors. If kidney cancer is suspected or diagnosed, it is recommended to go to regular hospitals for comprehensive assessment of the condition, follow the doctor’s instruction to cooperate with the treatment, and choose appropriate treatment plan to improve the prognosis of the patients, so as to avoid delaying the condition. Please strictly follow the doctor’s prescription for medication, and do not use medication on your own.