There are many causes of elevated prolactin, including physiological, pharmacological, and pathological elevations of prolactin, which cannot be treated clinically directly with medication, but need to be treated according to the cause in order to avoid re-elevation of prolactin. The physiological elevation is usually seen during the breastfeeding period and will gradually return to normal after the breastfeeding period is over, and generally does not require medication; the pharmacological elevation requires the reduction or discontinuation of the application of such drugs that cause elevated prolactin according to the doctor’s guidance; the pathological elevation has many common causes, and it is recommended to go to the hospital in a timely manner, and after a clear diagnosis, treat the cause under the doctor’s guidance, and not to blindly take oral medication on your own to avoid aggravating the condition or inducing other problems. The most important thing is to avoid aggravating the condition or inducing other discomforts. The main causes of drug and pathological elevation of prolactin are the following: 1. Drug elevation: oral contraceptives, cimetidine, chlorpromazine, synthetic thyrotropin-releasing hormone, and narcotics can increase the level of prolactin in the blood. At this time, it is recommended to adjust lifestyle habits, reduce or stop the application of such drugs according to medical advice, replace other drugs to treat the original disease or contraception, and regularly review the changes in prolactin levels to help adjust the treatment plan in a timely manner; 2. Pathologically elevated: Commonly found in pituitary prolactinomas, hypothalamic tumors, pituitary growth hormone tumors, which are treated clinically by different means, including surgery, drug The clinical treatment is carried out by different means, including surgery, drug therapy and stereotactic radiotherapy. Among them, for pituitary lactinomas, drug therapy is generally preferred, and the commonly used drugs include bromocriptine, pergolide, and carboxymetrine. In addition, lung metastasis of pituitary tumor, breast tumor, endocrine organ lesions, gonadal diseases and liver and kidney diseases can also cause elevated prolactin, and it is not recommended to treat them with medication. For example, breast tumors need to be surgically removed from the local lesions, and then chemotherapy or radiotherapy will be given to control the condition according to the nature of the tumor. In summary, there are many factors that trigger elevated prolactin, so it is recommended that after excluding physiological factors, you go to the hospital in a timely manner to avoid blindly using medication on your own, so as not to be the right medicine, delaying the best time to treat the disease or aggravating the condition.