Amyloidosis skin disease, mainly through drug treatment, if necessary, can also use physical therapy. 1. Drug treatment: oral antihistamines can be used for those with obvious itching; for those with generalized lesions, severe itching and poor control of antihistamines, procaine can be used for intravenous closure; avitamin A ester and thalidomide are effective for some patients. Local glucocorticoid sealing package or intradermal injection can relieve symptoms, but easy to recur after stopping the drug, 0.1% retinoic acid topical application can have a certain effect. 2. Physical therapy: you can also use liquid nitrogen freezing, laser treatment, etc., to promote the shedding of lesions, inhibit the growth of lesion cells. All of the above drugs should be used in accordance with the doctor’s instructions, do not self-medication. If you find yourself suffering from amyloidosis skin disease, it is recommended to go to the hospital, under the guidance of the doctor, choose the appropriate treatment.