The common clinical causes of axillary soreness and swelling are mainly the following: First, when the axilla is accompanied by benign masses such as epidermoid cysts or lipomas, as the volume of the mass increases, it may compress the axillary artery and axillary nerve in the axilla, thus causing local soreness and pain. At this time, the size and scope of the mass can be clarified through ultrasound examination, and complete excision of the mass can be performed as soon as possible to relieve the local neurovascular compression, which can improve the symptoms of soreness and swelling, and the pericardium of the mass can be completely excised during surgery to avoid residual masses, which can cause recurrent attacks later. Second, young women can cause soreness and discomfort in the lower armpit due to bilateral breast enlargement. At this time, the soreness and swelling symptoms in the armpit can be relieved by taking oral prolotherapy pills and Xiaojin tablets, applying hot towels and wet compresses to both mammary glands, acupressure and maintaining a good state of mind to reduce breast enlargement.