There is no specific value for how long one can live in the middle and late stage of liver cancer, and its survival period is related to the patient’s own condition, treatment means, sensitivity to treatment, etc., with large individual differences, so it cannot be generalized. According to the data, the 5-year survival rate of liver cancer in middle and late stages after active treatment is about 10%. Currently, the main treatment for liver cancer is surgery, including partial hepatectomy, liver transplantation, tumor ablation, transhepatic artery chemoembolization and other methods. Besides, it can also be combined with targeted therapy and chemotherapy. The focus of liver cancer treatment is early detection, early diagnosis and early treatment. The 5-year survival rate of early-stage liver cancer can reach 40%~60% after surgery, while the 5-year survival rate of middle and late-stage patients is about 10% after active treatment. It is recommended to consult doctor in time and actively cooperate with doctor’s treatment to prolong the survival and improve the prognosis of middle and late stage liver cancer.