Long-term Candesartan Hazards

Long-term consumption of candesartan may cause angioedema, hyperkalemia, acute renal failure and other hazards. 1. Angioedema: Candesartan is an angiotensin II receptor antagonist antihypertensive drug, which reduces blood pressure by antagonizing the vasoconstrictive effect of angiotensin II, thereby reducing peripheral vascular resistance, so it may cause angioedema in the face, throat, larynx and other parts of the body. 2. Hyperkalemia: Candesartan can inhibit the secretion of aldosterone by adrenal glands, thus reducing the excretion of potassium, thus causing hyperkalemia. 3. Acute renal failure: Candesartan can relax the small glomerular outflow arteries and reduce the glomerular capillary pressure, if the glomerular capillary pressure is too low, it will cause acute renal failure. Prolonged use of candesartan may also cause adverse reactions such as abnormal liver function, granulocyte deficiency, and rhabdomyolysis. Contraindications include patients with a history of hypersensitivity to the components of the drug, women who are pregnant or may become pregnant, and patients with severe hepatic or renal insufficiency or cholestasis. The specific use of the drug needs to be under the guidance of a professional physician, do not take on your own to avoid adverse reactions, resulting in adverse consequences.