Itchy blisters on the heel can be caused by two conditions, and the treatment is different depending on the situation. If it is eczema that causes redness, swelling and itching on the heel, usually dexamethasone ointment, salbutamol ointment or glycerite lotion is applied topically, and the symptoms can slowly improve. If the local friction and blister formation, due to the failure to deal with the wound and lead to local infection itchy, this situation must be anti-infective treatment, usually can be used externally erythromycin ointment, clindamycin ointment, Bactrim and other ointment to sterilize, disinfection treatment, and then oral antibiotics to strengthen the anti-inflammatory, disinfectant effect, which will be able to solve the problem. If the blisters are large, puncture must be given to drain out the water inside to heal faster.