Coronary angiography risks have some risk, but the vast majority of the risks are relatively small and mild. Coronary angiography risks can cause radial artery occlusion, mediastinal hematoma, contrast allergy, and contrast nephropathy, but the vast majority of the risks are not fatal enough. The actual most feared risk of coronary angiography is that of causing aortic root entrapment and acute occlusion of the coronary arteries, which is more risky or even fatal. The majority of the risks are related to the doctor’s proficiency and habits. Bad habits may lead to risks, such as not monitoring the pressure after entering the coronary artery, playing the amount of contrast agent or using more force or rough operation, which will increase the probability of risks. However, in general, the risk of fatalities may be 1/10,000, and the risk of coronary angiography is not very high, especially for skilled operators.