Fatty liver is the accumulation of fat in the liver due to various reasons, which causes elevated transaminases as well as symptoms such as abdominal distension and fatigue, poor appetite, and pain in the liver area. The transaminase elevation in patients with fatty liver is mainly mildly elevated, most of them are more than 2 times of the upper limit of normal value and less than 10 times of the upper limit of normal value, that is to say, the transaminase elevation in patients with fatty liver is seldom more than 400U/L, and 200-300U/L is the predominant one. Patients with elevated transaminases in fatty liver can regulate their diet and exercise appropriately, and they can take hepatoprotective and enzyme-lowering drugs for treatment, and the more commonly used ones in the clinic are silymarin, compound glycyrrhizin, and diammonium glycyrrhizinate.