It is not necessary to take anti-inflammatory drugs to treat mastocytosis. Mastocytosis is not an inflammatory disease, so the application of anti-inflammatory drugs is not effective. Mastocytosis is a proliferative disease that is neither inflammatory nor tumorigenic. It is essentially a disorder of the breast structure caused by hyperplasia and incomplete regeneration of the breast tissue. The main clinical symptoms of mastocytosis, including breast pain, breast lumps and nipple overflow, are not considered to be inflammatory diseases when breast pain occurs, but such pain is caused by tissue cell proliferation, and therefore is different from inflammatory diseases, and the application of anti-inflammatory treatment is not effective. For the treatment of breast hyperplasia, patients with mild symptoms often do not need to apply medication, but mainly let patients dynamically observe the changes of hyperplasia to see if there is any aggravation or further progress, because a small number of patients with hyperplasia may progress to breast cancer. For patients with severe breast enlargement, whose symptoms are particularly severe and obviously affect their life, they can be treated with medication or, in combination with local conditions, surgery if necessary. These treatments need to be further developed by a specialist and should not be applied at your own discretion.