Generally, membranous nephropathy caused by chronic viral hepatitis B is mostly caused by hepatitis B virus deposited in the kidneys, as well as including glomerulonephritis and other diseases. In this case, after active antiviral treatment, the patient’s condition will be improved or cured. These patients should have blood tests for hepatitis B DNA or hepatitis C RNA to see if there is any replication of hepatitis B. If there is replication of hepatitis B virus, the patient should have a blood test for hepatitis B DNA or hepatitis C RNA. If there is replication of hepatitis B virus, and combined with the elevation of ghrelin and ghrelin transaminase, it is considered that the patient is in the window period of viral replication. If the blood routine and other results are normal, we should actively consider antiviral treatment, and we can consider oral antiviral drugs or interferon injection for further antiviral treatment. If the kidney function test shows that the blood creatinine and urea nitrogen are elevated, it is more likely to consider the possibility of hepatorenal syndrome or the possibility of membranous disease. In this case, patients need to actively consider antiviral treatment, and actively be given hepatoprotective, diuretic and other treatments.