Blackheads on the nose are a symptom of acne, which is a skin lesion that manifests itself due to a blockage of the follicular opening that prevents sebum from being expelled. Acne is a common skin disease that is associated with abnormal androgen levels, blockage of the follicular opening, and propagation of Propionibacterium acnes. Sebaceous glands secrete oil. When sebum is produced in excess and is difficult to expel, it can accumulate in the follicles and form acne. When there are more sebaceous glands in the nose, oil and shed epithelial cells embolize the pores of the nose and there are openings on the skin surface. Sebum oxidizes in the air and turns black to form blackheads. When squeezed out, the top is black and the bottom is yellowish-white and transparent. Vitamin A drugs such as Adapalene and Tazarotene can be used as prescribed by the doctor to promote exfoliation and thus reduce the symptoms. Daily attention should be paid to cleaning the face, do not squeeze acne, so as not to cause infection. It is recommended that patients go to the hospital in a timely manner and receive standardized treatment under the guidance of a doctor.