Megacolon does not heal on its own with age, and once diagnosed, patients need to receive timely treatment. Megacolon is a common intestinal disease in pediatric patients, which is caused by congenital or acquired stenosis, weakened peristalsis or loss of peristaltic function of the distal colon, resulting in poor passage of feces and retention of feces in the anterior end of the colon, so that the intestinal tube becomes thicker and bigger, and it can be classified into congenital, pseudocongenital and idiopathic megacolon. Megacolon is more common in congenital, mostly due to intestinal nerve development disorders, lack of intestinal wall ganglion cells or partial reduction. Patients mainly manifest stubborn constipation, abdominal distension, dirty stools, etc., usually can not be self-cured, and long-term megacolon will also affect the growth and development of patients, so that patients appear developmental delay, wasting, anemia, malnutrition, and so on. Therefore, once the diagnosis is confirmed, it is necessary to consult a doctor in time and receive treatment actively to avoid delaying the condition. Currently, commonly used treatments include medication, surgery, anal dilation and improvement of lifestyle and diet.