The main cause of facial myospasm is the compression of the facial nerve root by intracranial blood vessels, resulting in facial and eye twitching, so relieving the compression of the facial nerve root is the key to treating the condition. For the treatment of facial spasm, the efficacy of drug therapy is minimal. Botulinum toxin injections are effective for some patients in the short term, usually lasting from 2-3 months to about six months before relapse, while repeated multiple injections or too large a dose at one time may lead to permanent local muscle paralysis. Microvascular decompression is currently the only internationally recognized effective method for the radical treatment of facial muscle spasm. The principle is to open the compressed neurovascular pad and release the compression of the blood vessels on the facial nerve root, thus achieving the purpose of radical treatment. For the treatment of Meige syndrome, it is still basically in symptomatic treatment, and for its radical treatment, there is still a lack of specific methods in domestic and foreign research. The treatment methods include oral medication, surgery, and local injection of botulinum toxin type A, etc. 1, oral drug therapy: oral drugs include: (1) dopamine receptor antagonists, such as haloperidol, Tebri, inosine, etc.; (2) γ-aminobutyric acid drugs, such as Jiajing Valium, sodium valproate, etc.; (3) anticholinergic drugs, such as Antan, etc.; (4) tranquilizers, such as diazepam, clonazepam, etc.; (5) antidepressants, such as amitriptyline, alprazolam, sertraline, etc. 2, type A botulinum toxin local injection treatment: type A botulinum toxin can not restore the cortical motor area and the ventral side of the pre-motor area damaged motor activity, but can make the local facial muscle movement caused by enhanced somatosensory activity partially normalized, indicating that type A botulinum toxin may have some significance for the recovery of brain function in this disease. type A botulinum toxin effect lasts for several weeks to several months, the main complication is local muscle paralysis. The drug is injected into the eyelids, perioral area and related areas of the face. About 30% of patients can have relief. 3, stereotactic minimally invasive surgery: for drug treatment is ineffective or less effective, or drug side effects are obvious, the patient’s symptoms obviously serious impact on life, neurosurgery intervention is also a more effective treatment options. The most advanced international treatment method is deep brain electrical stimulation (DBS), which is minimally invasive, reversible, adjustable and personalized, and is a safer and effective treatment with fewer side effects. The disadvantage is that it is currently more expensive. For patients with poorer economic conditions, stereotactic disruption of the deep brain nuclei is also an option.