A red bump on the buttocks that hurts when you touch it is usually considered folliculitis, or further become a boil, which needs active anti-infective treatment; in addition, it may also be caused by herpes zoster, which needs antiviral treatment. 1. Folliculitis or boils: red bumps on the top of the buttocks that hurt when you touch them are most often folliculitis or boils, which is usually an infectious inflammation of the hair follicles caused by Staphylococcus aureus infection, resulting in localized redness, swelling and pain. Boils can develop from folliculitis, which can develop as a result of untreated folliculitis that progresses deeper and around the area. If boils are not treated aggressively, they may further deteriorate into cellulitis, carbuncles, or localized abscess formation. Oral and topical antibiotics can be used for treatment, including oral cephalosporin and macrolide antibiotics, and topical mupirocin ointment. 2. Herpes zoster: a red bump on the buttocks that hurts when touched may also be herpes zoster, caused by varicella-zoster virus infection. It usually manifests as unilateral erythema and blisters, accompanied by severe pain. It can be treated by giving antiviral drugs such as acyclovir, and also by adding nutritive drugs such as methylcobalamin. There is a red bump on the buttock hurts when touched, it is recommended to consult a doctor in time, after clarifying the cause of treatment, the above drugs need to be used under the guidance of a doctor.