A thick nose can be caused by congenital heredity, fat and disease, and can be thinned by nose reduction, liposuction or medication. 1. Hereditary: some people have thick nose which is hereditary, just simple thick nose without any disease, then if you want to make it thinner, you can consider nose reduction surgery. 2. Fatty: some people with thick nose may have more fat, you can consider liposuction to suck out the excess fat from the nose to make the nose thinner. 3. Disease: some people have thick nose because of acquired organic lesions, such as rosacea, can be treated with medication, due to rosacea caused by thick nose, you can take oral antibiotics such as metronidazole, local application of isotretinoin cream and other drugs. The specific use of drugs need to be guided by a doctor. If you want to thin your nose, you can go to the hospital for examination before choosing the appropriate way.