The high mechanical strength of a blood clot indicates an abnormality in coagulation, which needs to be determined in the context of the condition. A blood clot is a semi-solid substance that appears red in color and is usually seen when the blood flow is slow. However, the presence of a clot with high mechanical strength suggests the presence of abnormal coagulation function. Diseases with abnormal coagulation function include hemophilia, aplastic anemia, idiopathic thrombocytopenia, etc. In addition, some degree of coagulation abnormality may occur after organ transplantation, acute trauma, and massive blood loss and transfusion. When there is a high intensity of blood clot mechanics, it is necessary to go to the hospital in a timely manner for coagulation examinations to clarify the state of coagulation function and the causes of coagulation abnormality, in order to target the development of treatment programs.