Chemoencephalitis is the abbreviation of purulent meningitis, which is a common infectious disease of the central nervous system, mainly due to inflammation of the brain caused by purulent bacterial infection. Clinical manifestations are mainly chills, high fever, patients have severe headache, frequent nausea and vomiting, severe patients may have consciousness disorder, coma, and some patients with focal symptoms, such as limb hemiparesis, aphasia. Other patients have limb convulsions or persistent epilepsy. Examination of the patient for cervical tonus, Kirschner’s sign and Buchner’s sign are positive, but Kirschner’s sign can also be negative in the elderly and comatose patients. Cerebrospinal fluid examination can find that the cell count is obviously elevated, cerebrospinal fluid pressure increases, usually given anti-infection, hormone therapy and lower intracranial pressure and other treatments, the patient’s symptoms can be relieved, but there are also patients with severe disease with a high mortality rate.