Muscle tissue biopsy has the significance of diagnosing myopathies, differentiating them from neurological diseases and determining whether systemic diseases involve muscle tissue.
1. Muscle tissue biopsy is often used to diagnose muscular diseases: myositis such as polymyositis, dermatomyositis; metabolic myopathies such as glycogen accumulation disease, Lafora disease; muscular dystrophy; congenital myopathies and so on.
2. Muscle tissue biopsy also has the significance of differential diagnosis, such as the identification of amyotrophic lateral sclerosis or other various myopathies resulting in muscle atrophy.
3. Myotissue biopsy can be used to clarify whether systemic diseases (such as endocrine myopathy) involve muscle tissue, or whether there are abnormal substances such as amyloid deposition in the interstitium.
To summarize, muscle tissue biopsy is of pivotal diagnostic significance in certain diseases, so patients should try to cooperate with the doctor to improve the examination, so as to facilitate the determination of the treatment plan.